Propolis has interesting antioxidant and anti-glycation properties to prevent age-related illnesses and complications of diabetes.
The propolis could enter natural anti-aging products. A French study reveals that experimentally the propolis allows reducing the level of potentially toxic compounds called advanced glycation endproducts or AGE.
Propolis is a resin that coats the buds of some trees. The bees take the propolis on the buds of the trees by collecting it on their hind legs and bringing it back to the hive.
The AGE, which are brought by certain foods or made by the body in diabetes, plays a role in diseases such as Alzheimer’s. They are the cause of the complications of diabetes such as retinopathy and nephropathy. The AGE also increases oxidative stress, which is another form of aggression against cells and organs.
In this French study, several propolis extracts showed very good anti-aging and antioxidant effects. The analyses revealed the most active compound is a substance called pinobanksin-3-acetate.
A Croatian study of 2012 found propolis decreases renal damage in a model of diabetic nephropathy among mice.
The propolis could therefore be interesting in the prevention of certain chronic diseases and in diabetics. Other substances having shown an effect against AGE include alpha-lipoic acid, carnosine, vitamin B6, aminoguanidine, folates. Vitamin E could help control some of the harmful cellular consequences of AGE.
Boisard S, Le Ray AM, Gatto J, Aumond MC, Blanchard P, Derbré S, Flurin C, Richomme P. Chemical Composition, Antioxidant and Anti-AGEs Activities of a French Poplar Type Propolis. J Agric Food Chem. 2014 Feb 12;62(6):1344-51.